Lung transplant is usually done in patients with non-malignant advanced or end-stage pulmonary diseases (such as severe pulmonary fibrosis, cystic fibrosis, pulmonary hypertension and obliterative bronchiolitis) that is minimally responsive or unresponsive to treatment and who have a life expectancy of less than a year. This improves patients' quality of life and prolongs survival.
Ex-situ machine perfusion for extracorporeal preservation of lungs (ex-vivo lung perfusion, EVLP) is a technique ...
Evidence on the safety and efficacy of inducing and maintaining normothermia using temperature modulation devices to improve outcomes after stroke or subarachnoid haemorrhage is inadequate in quality and quantity. Therefore, this procedure should only be used in the context of research.
Fecal incontinence is an inability to control bowel movements, resulting in the involuntary passage of stool. The defecation process and its control is complex. Causes of incontinence include problems with the colon and rectum, problems with the sphincter muscles, or nerve damage.
Fecal incontinence can also be caused by loss of higher-level brain control in conditions such as dementia or severe learning disability.
The initial management of faecal incontinence includes interventions related ...
Heart failure is a complex clinical syndrome of symptoms and signs that happen when the heart is not working well enough. It leads to reduced blood flow to body tissues and can cause oedema in the lungs (causing breathlessness) and swelling of the legs. Other symptoms include reduced ability to exercise, fatigue and malaise. Heart failure can be caused by structural or functional abnormalities of the heart. The aim of implanting a permanent pacemaker at the His bundle is to produce normal ...
Obsessive-compulsive disorder (OCD) is a mental health condition in which a person has obsessive thoughts (repeated, unwanted and unpleasant thoughts, images or urges). The person feels compelled to carry out compulsive (repetitive) behaviours to try to relieve the unpleasant feelings brought on by the obsessive thoughts.
Deep brain stimulation for OCD is done under general or local anaesthesia. A stereotactic frame may be used. MRI or CT imaging, or both, are used to identify the target area ...