Canadian Society of Allergy and Clinical Immunology
The presence of IgG to a specific food indicates previous exposure not hypersensitivity. The use of methods other than serum-specific IgE evaluation or skin prick testing in diagnosing allergies is not proven and can result in inappropriate diagnosis and treatment.
Among patients with type 2 diabetes who have established atherosclerotic cardio- vascular disease or established kidney disease, a sodium–glucose cotransporter 2 inhibitor with proven benefit in this patient population is recommended to reduce the risk of major adverse cardiovascular events and/or heart failure hospitalization, reducing the risk of worsening heart failure and cardiovascular death.
There are no maintenance treatments routinely available for advanced ovarian, fallopian tube or peritoneal cancer that has responded to first-line platinum-based chemotherapy. Clinical evidence comes from PRIMA, an ongoing clinical trial, which shows that niraparib delays disease progression. But it has not shown whether people having niraparib live longer because they have not been followed up for long enough.
Usual treatment for age-related macular degeneration is aflibercept and ranibizumab. The evidence that brolucizumab provides similar overall health benefits to these drugs, and is similarly safe, has been drawn from clinical trials and network meta-analyses. Brolucizumab will be recommended, only in cases where the eye to be treated has the best-corrected visual acuity between 6/12 and 6/96, there is no permanent structural damage to the central fovea, the lesion size is less than or equal to ...
Leukomed Sorbact is an interactive dressing that binds to the microbes that cause surgical site infection so they are removed when the dressing is changed.
Leukomed Sorbact should be considered as an option for people with wounds that are expected to have low to moderate exudate after caesarean section and vascular surgery. It should be used as part of usual measures to help reduce the risk of surgical site infection. More evidence is needed on the use of Leukomed Sorbact on wounds after other ...