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Consider using recruitment manoeuvres for mechanically ventilated adults with COVID-19 and hypoxaemia despite optimising ventilation
Evidencias COVID-19
National COVID-19 Clinical Evidence Task Force
Patients receiving respiratory support are at an increased risk of lung injury. Recruitment manoeuvres are used to open up (‘recruit’) collapsed alveoli and are a common element of an ‘open lung approach’ to protect the lungs during mechanical ventilation. The manoeuvres use a sustained increase in airway pressure to re-open collapsed alveoli. Types of manoeuvres include: prolonged high continuous positive airway pressure; progressive incremental increases in positive end-expiratory ...
ver más ... 2020Consider using a higher positive end-expiratory pressure (PEEP > 10 cm H2O) over a lower PEEP strategy for mechanically ventilated adults with COVID-19 and moderate to severe ARDS.
Evidencias COVID-19
National COVID-19 Clinical Evidence Task Force
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ver más ... 2020Consider using videolaryngoscopy over direct laryngoscopy, if available and the operator is trained in its use in adults with COVID-19 undergoing endotracheal intubation.
Evidencias COVID-19
National COVID-19 Clinical Evidence Task Force
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ver más ... 2020It is uncertain whether Lopinavir / ritonavir is an effective treatment for COVID-19.
Evidencias COVID-19
Epistemonikos Foundation
Lopinavir / ritonavir may slightly decrease mortality in low or moderate risk patients (low certainty of evidence) and in high risk patients may decrease mortality (low certainty of evidence) Studies show that it could decrease the risk of developing respiratory failure or acute respiratory distress syndrome, lead to a slight clinical improvement at 14 days, and make no difference in the length of hospitalization (low evidence certainty) Lopinavir / ritonavir may not be associated with a ...
ver más ... 2020It is uncertain that stem cells are effective in the treatment of COVID-19.
Evidencias COVID-19
Epistemonikos Foundation
There are no studies that specifically evaluate its usefulness in COVID-19. Studies evaluating its usefulness in other infections, and whose information could be extrapolated to COVID-19, provide very low certainty evidence. The use of stem cells as a Covid-19 treatment has small risks; however, the benefits are uncertain, the costs potentially high, and may possibly lead to associated problems. Therefore, it is highly unlikely that stem cells are scientifically recommended.
ver más ... 2020