Cochrane Portugal - Institute for Evidenced Based Health
In this population-based study in Italy (Lombardy), 6,272 cases of SARS-CoV-2 infection were compared with 30,759 uninfected patients (controls). There does not appear to be any risk of Covid-19 in patients taking enzyme inhibitors. conversion of angiotensin (ACE), and / or angiotensin receptor blockers, and / or beta-blockers, and / or calcium channel antagonists and / or thiazide diuretics. Therefore, discontinuation of treatment with these medicinal products is not justified, for example, ...
Cochrane Portugal - Institute for Evidenced Based Health
The situation becomes even more serious for health professionals. The consequences of quarantine on mental health can be very serious, with enormous uncertainty about its long-term impact, since in the history of humanity people without diseases have never been isolated. Future measures to resolve the crisis should take into account this dramatic reality.
We followed the Cochrane rapid review methodology The search strategy encompasses one academic database until April 1, 2020. 21 manuscripts were identified that met the inclusion criteria. Of six systematic reviews, four found no reduction in the probability of transmission. Experimental home studies found no differences in the probability of contagion associated with the use of mouth masks. Only one modeling study estimated a 20% reduction in the incidence of acute respiratory disease, ...
Where severe acute kidney disease is present, unfractionated heparin or renally adjusted doses of LMWH may be used (e.g. enoxaparin 20 mg once daily or dalteparin 2500 IU once daily).