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It is uncertain whether the use of antimalarial drugs has an effect in the treatment of COVID-19 pneumonia.
Evidencias COVID-19
Epistemonikos Foundation
It is not possible to establish clearly whether the use of antimalarial drugs in the treatment of COVID-19 pneumonia has any effect on outcomes such as mortality or the requirement for mechanical ventilation. It is not possible to establish clearly whether adding antimalarial drugs to standard treatment reduces the risk of developing respiratory failure Adding antimalarials to standard treatment may increase the incidence of serious adverse effects Adding antimalarials may not even have an ...
ver más ... 2020Currently, there is uncertain evidence on the effectiveness of chloroquine or hydroxychloroquine in COVID-19
Evidencias COVID-19
Epistemonikos Foundation
China grouped the authors of 15 ongoing clinical studies. It was announced that they had concluded that chloroquine has potent activity against COVID-19 but to date none of these studies have reported their results. On the other hand, a non-randomized study was developed in France that has been critically analyzed by several experts worldwide and was found to have enormous methodological limitations. After a systematic review of all the existing literature, no other study with available ...
ver más ... 2020It is uncertain that enalapril, losartan and other drugs that act on the renin angiotensin aldosterone system increase or decrease the risk in patients exposed to COVID-19 or in those infected.
Evidencias COVID-19
Epistemonikos Foundation
There are no human studies that present conclusive results. The only study identified in humans showed no effect (neither in favor nor against). This constitutes preliminary evidence, so it is currently not possible to establish clearly whether these drugs increase or decrease the risk, or have no effect, in patients at risk of contracting COVID-19 or in those infected. Furthermore, the evidence alone is never enough to make decisions. The balance between benefits and risks, the associated ...
ver más ... 2020Consider early endotracheal intubation and invasive mechanical ventilation in patients with COVID-19 who are deteriorating.
Evidencias COVID-19
National COVID-19 Clinical Evidence Task Force
Please visit the link for more information
ver más ... 2020Do not use non-invasive ventilation therapy during inter-hospital patient transfer/retrieval, for patients with hypoxaemia associated with COVID-19
Evidencias COVID-19
National COVID-19 Clinical Evidence Task Force
Non-invasive ventilation (NIV), also known as non-invasive positive pressure ventilation (NIPPV) or bilevel positive pressure support (BiPAP), is a form of respiratory support. Bilevel positive pressure is delivered throughout the respiratory cycle by a firm-fitting nasal-face mask. The patient breathes spontaneously and triggers the device to cycle. A higher level of pressure is provided during the inspiratory phase to enhance ventilation, while a lower level of continuous positive pressure ...
ver más ... 2020