IHCAI – DIME. Información seleccionada sobre intervenciones para el tratamiento de COVID-19
Under the premise that hydroxychloroquine has been widely administered to patients with Covid-19 without strong evidence to support its use, an observational study was conducted with a cohort of 1,376 patients in New York (NY), USA. The association between hydroxychloroquine use and respiratory failure at a large medical center that cares for a considerable number of Covid-19 patients in NY was examined. The use of hydroxychloroquine was presumed to be associated with a lower risk of a ...
Coronavirus (COVID-19): Evidence Collection. Evidence Aid
Some patients with COVID-19 will become critically ill and need help with their breathing. They may be given extra oxygen to breathe, which might be provided by mechanical ventilation (MV) in an intensive care unit (ICU). Clinicians need to decide on the amount of supplemental oxygen to use.
There is a Cochrane systematic review, where the authors searched for randomized trials of the effects of different levels of supplemental oxygen in adult ICU patients. They identified 10 studies (1458 ...
Coronavirus (COVID-19): Evidence Collection. Evidence Aid
Most people with COVID-19 will develop a persistent cough and some may develop pneumonia. Non-prescription, over-the-counter (OTC) medicines have been used in the past to help with this in people without COVID-19. However, suppression of the cough mechanism might impede airway clearance and cause harm.
There is a Cochrane systematic review, where the authors searched for randomised trials testing OTC cough medications in children and adults with cough that was secondary to acute pneumonia for ...
Coronavirus (COVID-19): Evidence Collection. Evidence Aid
Most people with COVID-19 will develop a persistent cough. Non-prescription, over-the-counter (OTC) medicines are often used to treat cough in children and adults.
In the Cochrane systematic review, the authors searched for randomised trials of OTC cough preparations in children and adults with acute cough. They identified 10 placebo-controlled randomised trials in children (1036 participants) and 19 placebo-controlled randomised trials in adults (3799 participants).
There is insufficient ...
Coronavirus (COVID-19): Evidence Collection. Evidence Aid
COVID-19 is a viral infection of the respiratory tract. Oral ribavirin has been suggested for the treatment of other non-influenza respiratory viral infections.
In this systematic review, the authors searched for research into the clinical outcomes of patients treated with oral ribavirin for symptomatic non-influenza respiratory viral infections. They identified 12 retrospective and 3 prospective studies. There were no randomized or controlled prospective studies.
Oral ribavirin may improve ...