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Evidencias COVID-19

IHCAI – DIME. Información seleccionada sobre intervenciones para el tratamiento de COVID-19

Ivermectin is a drug that has been tested in vitro and is being studied in clinical trials being conducted in Australia among other countries. This publication reports that Ivermectin, an FDA-approved antiparasitic that previously was shown to have broad-spectrum antiviral activity in vitro, is an inhibitor of the causative virus (SARS-CoV-2), with a single addition to Vero-hSLAM cells, 2 hours after infection with SARS-CoV-2 capable of effecting a veces5000 fold reduction in viral RNA at 48 h. ...

Evidencias COVID-19

IHCAI – DIME. Información seleccionada sobre intervenciones para el tratamiento de COVID-19

Several alerts have been published on the use of nonsteroidal anti-inflammatory drugs for patients with COVID 19. The Quick Review found no RCTs. She reviewed 5 observational studies compiled by the Oxford Center for Evidence-Based Medicine (CEBM). It should be noted that the duration of treatment (acute or chronic) with NSAIDs in the studies is not clear in the review. Available evidence suggests that although the anti-inflammatory effects of NSAIDs reduce acute symptoms (such as fever), they ...

Evidencias COVID-19

IHCAI – DIME. Información seleccionada sobre intervenciones para el tratamiento de COVID-19

Given the important concern of the use of IECAs and ARA II in patients with hypertension diagnosed with COVID-19. This multicenter retrospective study included 1,128 adult patients with hypertension diagnosed with COVID-19, including 188 who took IECAS / ARA II, sought to determine the association between hospital use of IECAS/ ARA II and all-cause mortality in patients with hypertension. arterial COVID-19. In conclusion, although patients hospitalized for COVID-19 with hypertension, hospital ...

Evidencias COVID-19

IHCAI – DIME. Información seleccionada sobre intervenciones para el tratamiento de COVID-19

The authors conclude that vitamin D levels are very low in the aging population, especially in Spain, Italy and Switzerland. They found significant relationship between vitamin D levels and the number COVID-19 cases and especially the mortality caused by this infection. This is also the most vulnerable population group for COVID-19, likewise, they consider that the use of vitamin D supplements should be recommended to protect against SARS-CoV2 infection. The authors only study in European ...

Evidencias COVID-19

IHCAI – DIME. Información seleccionada sobre intervenciones para el tratamiento de COVID-19

There have been several publications about the use of some compounds that are considered antioxidants that may have some effectiveness in respiratory diseases. In daily practice, the population uses vitamin C (ascorbic acid) in different presentations for its management. In this publication (Cheng, 2020) recommends its use based on some observational studies. It should be remembered that there is a Cochrane Review that demonstrates the low effectiveness of Vitamin C in the common cold. The ...