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NICE

NICE

Endoscopic sleeve gastroplasty is a minimally invasive transoral endoscopic procedure that reduces the volume of the stomach and may delay gastric emptying. It creates a sensation of fullness and reduces the amount of food that can be eaten at one time. Evidence on safety shows this procedure is safe in the short and long term. Evidence on efficacy shows that, when combined with lifestyle changes, people with a body mass index (BMI) over 30 kg/m2 who have the procedure lose weight. So, it can ...

NICE

NICE

In the management of suspected sepsis in acute hospital settings in patients over 16 years of age at risk of severe illness or death, it is recommended that a physician with basic competencies in acute illness evaluate the patient, as well as perform a blood test. which includes: blood gases, including measurement of glucose and lactate, blood culture, complete blood count, C-reactive protein, urea and electrolytes, creatinine, liver function tests and a coagulation study. It is also ...

Less Is More Collection - JAMA Network

JAMA Network

Single case study that describes the situation of a woman with adverse effects from taking digoxin. Symptoms and signs were chest pain, nausea, anorexia and fatigue.

NICE

NICE

Evidence from clinical trials suggests that sebelipase alfa increases the life expectancy of patients with Wolman's disease (rapidly progressive lysosomal acid lipase deficiency), a rare genetic condition that occurs in infants and children under 2 years of age. It causes a buildup of fat in the cells of the liver, heart, blood vessels and digestive system. Without treatment, the infant or child will not survive. With sebelipase alfa treatment, it is unclear how much longer these patients will ...

U.S. Preventive Services Task Force A and B recommendations

USPSTF

Delays and disorders of speech and language can pose significant problems for children and their families. Evidence suggests that school-age children with speech or language delays may be at increased risk for learning and literacy disabilities, including reading and writing difficulties. Observational cohort studies suggest that children with these conditions may also be at increased risk for social and behavioral problems as well as learning problems, some of which may persist into ...