Cochrane Portugal - Institute for Evidenced Based Health
It is possible to state that, with the results of this systematic review based on low quality evidence, full-body PPE protects against microbial contagion, but presents discomfort to dress and undress. Training in the handling of this equipment appears to be effective in adhering to clinical practice guidelines. For greater user satisfaction, a technical evolution of the currently available PPE will be necessary.
Cochrane Portugal - Institute for Evidenced Based Health
The safety profile of the most common vaccines is excellent, with clinically insignificant side effects. Pharmacovigilance systems have proven crucial to have an accurate idea of risk. To ensure the safety of SARS-CoV-2 vaccines, R&D methodologies must follow the usual steps.
There is no certainty about the relationship between treatment-induced viral clearance and its effect on clinical outcomes.
The clinical impact of antimalarial treatment is uncertain. Indeed, an interim analysis in a large RCT, recommending continued randomization to this treatment, showed a statistically different effect from the excess risk identified by a large observational study.
Based on studies of previous outbreaks, individual, organizational and social factors were identified that favored or reduced the risk of psychological impact.
Risk factors for psychological impact can be addressed with preventive or mitigation strategies applied in previous outbreaks of emerging viruses.