Multiple sclerosis is an acquired chronic immune-mediated inflammatory condition of the central nervous system, affecting both the brain and spinal cord. It is the most common cause of serious physical disability in adults of working age.
The guideline is aimed primarily at services provided in primary and secondary care. It covers diagnosing and managing multiple sclerosis in people aged 18 and over. It aims to improve the quality of life for people with multiple sclerosis by promoting prompt ...
UTI is a common bacterial infection that causes illness in babies and children. It can be difficult to recognize UTI in children because the presenting symptoms and signs are not specific, particularly in babies and children under 3 years.
Symptoms and signs that increase the likelihood that a urinary tract infection (UTI) is present:
-Painful urination (dysuria)
-More frequent urination
-New bedwetting
-Foul smelling (malodorous) urine
-Darker urine
-Cloudy urine
-Frank haematuria (visible ...
NICE did a rapid review of the published literature on the efficacy and safety of this procedure. The evidence included 2 systematic reviews, 1 non-randomised comparative study, 2 cohort studies, 1 single-arm study that was also included in the systematic reviews, a case report, and a case series of reports from the US Food and Drug Administration Manufacturer and User Facility Device Experience Databased. This procedure is primarily intended to be used for people with unfavourable aneurysm ...
Short-term evidence shows no major safety concerns, but long-term evidence on safety is limited in quality and quantity. Therefore, this procedure should only be used with special arrangements for clinical governance, consent, and audit or research.
There was little evidence about the people for whom the procedure is most appropriate, particularly the stage of osteoarthritis at which it should be used. They used a rapid review of the published literature on the efficacy and safety of this procedure. The evidence included 1 randomised controlled trial (described in 2 papers), 4 non-randomised comparative studies, 7 case series, 1 case report and a review of adverse events from the US Food and Drug Administration Manufacturer and User ...