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NICE

National Institute for Health and Care Excellence

RPE65-mediated inherited retinal dystrophies are rare and serious. They involve progressive loss of vision. This ultimately leads to near-total blindness, and severely affects the quality of life of people with the condition, and their families and carers. Current treatment is supportive care. Clinical trial evidence shows that, in the short term, voretigene neparvovec improves vision and prevents the condition from getting worse. There is no long-term clinical evidence, but it is biologically ...

NICE

National Institute for Health and Care Excellence

This recommendation is not intended to affect treatment with fluocinolone acetonide intravitreal implant that was started in the NHS before this guidance was published. People having treatment outside this recommendation may continue without change to the funding arrangements in place for them before this guidance was published, until they and their NHS clinician consider it appropriate to stop. Treatments for untreated chronic diabetic macular oedema include laser therapy and anti-vascular ...

Iniciativa MAPAC (Mejorar la Adecuación de la Práctica Asistencial y Clínica)

Interventional procedures guidance

The evidence on efficacy is adequate in quality and quantity.

Iniciativa MAPAC (Mejorar la Adecuación de la Práctica Asistencial y Clínica)

National Institute for Health and Clinical Excellence (NICE)

In the case of pacients with recurrent episodies who choose medication, they must be treated with the following warnings: -the risk of developing complications underlying conditions (such as oedema, diabetes or venous insufficiency) and their management. -the risk of resistance with long-term antibiotic use.

Iniciativa MAPAC (Mejorar la Adecuación de la Práctica Asistencial y Clínica)

Diagnostics guidance

This is because their effect on improving antimicrobial prescribing and stewardship, and on patient outcomes, as compared with clinical scoring tools alone, is likely to be limited. Therefore, they are unlikely to be a cost-effective use of NHS resources.