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NICE

NICE

Osteoarthritis is characterized by localized loss of cartilage, remodeling of adjacent bone, and associated inflammation. The knees are one of the most affected joints, with pain being an important symptom. Radiofrequency denervation involves applying thermal energy (radiofrequency) to damage the nerves (denervation) that cause knee pain. There is good evidence that this procedure relieves pain in the short term.

NICE

NICE

FibroScan is recommended to assess liver fibrosis and cirrhosis if each FibroScan device is expected to be used for at least 500 scans per year, this is likely to improve access to testing for underserved groups, used in accordance with guidelines national standards, a clear care pathway is set out locally with guidance for professionals, there is training for healthcare professionals on how to perform the test, and the company provides support materials to ensure that people using the test ...

NICE

NICE

Hypertension is a major risk factor for cardiovascular disease and chronic kidney disease. Hypertension can be primary or secondary. Aortic valve disease (stenosis or regurgitation) is usually progressive and causes increased cardiac workload, left ventricular hypertrophy, and heart failure. Symptoms may include palpitations, fatigue, shortness of breath, syncope, and chest pain with exercise. The NICE guideline on hypertension in adults outlines the diagnosis and treatment of hypertension, ...

NICE

NICE

There is insufficient evidence to recommend routine adoption of automated ankle-brachial pressure index (ABPI) measurement devices to detect peripheral arterial disease in people with leg ulcers. They should only be used in the context of research in these people. Centers that already use automated ABPI measurement devices to detect peripheral arterial disease in people with leg ulcers may continue to use them only if: They collect data or conduct research to evaluate their value and how well ...

NICE

NICE

Erythropoietic protoporphyria is a condition in which exposure to light causes very painful and debilitating reactions in the body. There is no treatment and the only way to avoid reactions is to avoid light. There is some evidence from clinical trials that afamelanotide provides benefits to people with this disease. Despite this, the benefits of afamelanotide may not have been adequately captured in the formal analysis and therefore it is not possible to conclude that afamelanotide provides ...