National Institute for Health and Clinical Excellence (NICE)
A catheter-associated urinary tract infection (UTI) is a symptomatic infection of the bladder or kidneys in a person with a urinary catheter.
The longer a catheter is in place, the more likely bacteria will be found in the urine; after 1 month nearly all people have bacteriuria.
Antibiotic treatment is not routinely needed for asymptomatic bacteriuria in people with a catheter.
Give advice about managing symptoms with self-care.
National Institute for Health and Clinical Excellence (NICE)
An acute exacerbation of chronic obstructive pulmonary disease (COPD) is a sustained worsening of symptoms from a person's stable state
A range of factors (including viral infections and smoking) can trigger an exacerbation
Many exacerbations (including some severe exacerbations) are not caused by bacterial infections so will not respond to antibiotics
Some people at risk of exacerbations may have antibiotics to keep at home as part of their exacerbation action plan (see the recommendations on ...
National Institute for Health and Clinical Excellence (NICE)
Be aware that an acute exacerbation of bronchiectasis is a sustained worsening of symptoms from a person's stable state.
Obtain a sputum sample from people with an acute exacerbation of bronchiectasis and send for culture and susceptibility testing.
Offer an antibiotic to people with an acute exacerbation of bronchiectasis.
When results of sputum culture and susceptibility testing are available:
- Review the choice of antibiotic and
only change the antibiotic according to susceptibility ...
National Institute for Health and Clinical Excellence (NICE)
Current treatments for low-risk prostate cancer include active surveillance and, for people whose disease has progressed (usually beyond low-risk disease), radical therapies such as surgery and radiotherapy. Focal therapies such as cryotherapy and high-intensity focused ultrasound can also be used, but are not routinely available.
Professional organisations and NHS England say that there is a growing trend for people with low-risk disease to have active surveillance rather than radical therapy. ...
National Institute for Health and Clinical Excellence (NICE)
NETs can affect the pancreas and gastrointestinal tissue and are difficult to diagnose and treat. Current treatment options include everolimus, sunitinib and best supportive care.
Clinical trial evidence shows that lutetium (177Lu) oxodotreotide (referred to as lutetium) is effective for treating somatostatin receptor-positive gastrointestinal and pancreatic NETs. Indirect comparison with everolimus, sunitinib and best supportive care suggests lutetium is effective for treating gastrointestinal ...