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NICE

NICE

The aim of maximal cytoreductive surgery for advanced ovarian cancer is to safely remove all identifiable disease, to improve survival, compared with surgery that leaves residual disease. It is a development and extension of standard surgery for ovarian cancer. Evidence on the safety and efficacy of maximal cytoreductive surgery for advanced ovarian cancer is adequate to support using this procedure

NICE

NICE

Primary hyperoxaluria type 1 is a rare inherited disease that can significantly affect the quality of life of people who suffer from it, their families and caregivers. In primary hyperoxaluria type 1, the liver produces excess oxalate that combines with calcium in the tissues to form toxic crystals. These crystals can cause recurrent kidney stones, kidney damage, and in severe cases, kidney failure and multi-organ damage. Standard care includes supportive measures, dialysis, and a liver and ...

NICE

NICE

Obstructive sleep apnoea is a condition in which the upper airway narrows or closes during sleep when the throat muscles intermittently relax. This causes reduced breathing (hypopnoea) or breathing to temporarily stop (apnoea). OSA can lead to major neurocognitive and cardiovascular sequelae. Management of OSA includes lifestyle changes (such as weight loss), continuous positive airway pressure, oral devices (mandibular advancement devices), neuromuscular electrical stimulation and upper ...

Essencial: Afegint valor a la pràctica clínica [Essencial: Adding value to the clinical practice]

Generalitat de Catalunya

In general, the concomitant treatment of opioids and gabapentinoids (gabapentin and pregabalin) in people with chronic non-cancer pain is considered a practice of little value. The reason is that the effectiveness of this combination is uncertain compared to monotherapy with either, and it increases the risk of respiratory depression or opioid overdose. Clinical practice guidelines and consensus documents recommend paying special attention to the combined prescription of opioids and ...

NICE

NICE

Evidence on the safety and efficacy of radiofrequency ablation for palliation of painful spinal metastases is limited in quantity and quality. Therefore, this procedure should only be used with special arrangements for clinical governance, consent, and audit or research. Clinicians wanting to do radiofrequency ablation for palliation of painful spinal metastases should: - Inform the clinical governance leads in their healthcare organisation. - Give people (and their families and carers as ...