National Institute for Health and Clinical Excellence (NICE)
In people who cannot tolerate chemotherapy or have liver metastases that are refractory to chemotherapy, there is evidence of efficacy but this is limited, particularly for important outcomes such as quality of life. Therefore, in these people, this procedure should only be used with special arrangements for clinical governance, consent, and audit or research.
In people who can have chemotherapy, evidence on overall survival and quality of life is inadequate in quality. Therefore, in these ...
National Institute for Health and Clinical Excellence (NICE)
Surgical instruments that come into contact with high-risk tissues must not be moved from one set to another and must remain within their individual sets. Maintaining set integrity reduces the risks associated with instrument migration (including infection) and makes it easier to trace instruments back to the patients they were used on.
Supplementary instruments that come into contact with high-risk tissues must remain within the individual set to which they have been introduced. Supplementary ...
National Institute for Health and Clinical Excellence (NICE)
Patient selection should be done by a specialist hepatobiliary cancer multidisciplinary team that can offer the full range of treatment options for this condition.
National Institute for Health and Clinical Excellence (NICE)
There are many causes of leg ulcers: underlying conditions, such as venous insufficiency and oedema, should be managed to promote healing.
Most leg ulcers are not clinically infected but are likely to be colonised with bacteria.
Antibiotics do not help to promote healing when a leg ulcer is not clinically infected.
Do not take a sample for microbiological testing from a leg ulcer at initial presentation, even if it might be infected.
Only offer an antibiotic for adults with a leg ulcer when ...
National Institute for Health and Clinical Excellence (NICE)
1.1.1. People with impetigo, and their parents or carers if appropriate, about good hygiene measures to reduce the spread of impetigo to other areas of the body and to other people.
1.1.2. Consider hydrogen peroxide 1% cream for people with localised non-bullous impetigo who are not systemically unwell or at high risk of complications. Although other topical antiseptics are available for treating superficial skin infections, no evidence was found for using them to treat impetigo.
1.1.3. If ...