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It is recommended to use a multifaceted approach (e.g. the use of masks during high risk exposure and the practice of evidence-based hand hygiene techniques) to prevent the transmission of ...
Evidencias COVID-19
JBI COVID-19 Special Collection
(Grade A) This evidence summary is based on a structured search of the literature and selected evidence-based health care databases. The evidence in this summary comes from: • A systematic review (part of a series of four systematic reviews) of 10 RCTs.1 • A systematic review of 17 studies (8 RCTS – five in community settings and three hospital-based studies, and nine observational studies – seven conducted among healthcare workers and two community-based studies).2 • A systematic ...
ver más ... 2020There is no certainty to discontinue ACEI or ARA-II treatments due to fear of COVID-19 infection
Evidencias COVID-19
Cochrane Navarra - Sección de Innovación y Organización del SNS-O
- The scientific literature that supports the use of ACEI or ARA-II in hypertensive patients to obtain an alleged benefit against COVID-19 infection is scarce and of low quality evidence. - The hypotheses of potential benefit are based on experience with a previous virus (SARS-CoV), have been tested primarily in animal or in-vitro models and include both ACEI and ARA-II. - There is a potential risk of severe hypotension in patients hospitalized with respiratory failure and receiving treatment ...
ver más ... 2020It is uncertain if masks under normal exhalation conditions (with or without spontaneous cough) could limit the transmission of SARS-CoV-2, additional studies are required in different settings to ...
Evidencias COVID-19
Centro Cochrane Iberoamericano
Recently it has been shown that exhalation, coughing and sneezing can have a turbulent multi-phase behavior, leading to an emission of particles of multiple sizes. The persistence of SARS-CoV-2 particles has also been shown both in the personal belongings of people with COVID-19, and in the environments in which they have remained. This justifies the need to evaluate the use of masks to see if they can reduce the transmission of SARS-CoV-2. A clinical trial that, among others, included 11 ...
ver más ... 2020Don’t prescribe unproven therapies for COVID-19 patients other than in an approved clinical trial.
Choosing Wisely Canada
Choosing wisely Canada
There is no formal consensus between clinician groups regarding treatment of COVID-19 and evidence is evolving. Treating patients outside of clinical trials will limit our collective ability to scientifically assess treatment efficacy and put patients at risk of harm from drugs. Monitored compassionate use approaches may be acceptable in some jurisdictions.
ver más ... 2020Don’t intubate frail elderly patients in the absence of a discussion with family members regarding the patient’s advance directives whenever possible.
Choosing Wisely Canada
Choosing wisely Canada
In the COVID-19 pandemic, these decisions must be made urgently, hopefully based on prior discussions. Frail elderly patients who are sick enough to require intubation for any reason, including COVID-19, have very poor survival outcomes and poor quality of life. Early conversations with patients and families help to prevent rushed decisions or ones that do not reflect patient wishes.
ver más ... 2020