National Institute for Health and Clinical Excellence (NICE)
This recommends that SIRT should only be offered:
- With special arrangements for clinical governance, consent, and audit or research to people who are chemotherapy intolerant or who have liver metastases that are refractory to chemotherapy
- In the context of research to people who can have chemotherapy.
National Institute for Health and Clinical Excellence (NICE)
Offer preoperative radiotherapy or chemoradiotherapy to people with rectal cancer that is cT1-T2, cN1-N2, M0, or cT3-T4, any cN, M0.
There was no evidence for the effectiveness of preoperative radiotherapy for people with early rectal cancer, and based on their experience the committee would not recommend preoperative radiotherapy. However, the ongoing STAR-TREC trial, which is a multicentre randomised controlled trial, compares radiotherapy to TME for early rectal cancer. Because of this, the ...
National Institute for Health and Clinical Excellence (NICE)
Removing the requirement to use different instruments on high-risk tissues for people born after 1996 would not markedly increase the risk of surgical transmission of CJD.