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The transition from a situation of generalized transmission in the community to a stable state of low level or without transmission, supported by data and to be implemented gradually is recommended.
Evidencias COVID-19
Centro Cochrane Iberoamericano
In the absence of a safe and effective vaccine, the best result to be expected in the short and medium term in countries with a community transmission scenario is to achieve a sustained state of low or no transmission of COVID-19. Achieving this goal will depend on the authorities' ability to ensure that six key criteria are met: 1- Transmission of COVID-19 is controlled at a level of sporadic cases and grouped cases, all from known or imported contacts, and the incidence of new cases remains ...
ver más ... 2020There is no reliable information on the use of Remdesivir as a potential therapy against COVID-19.
Evidencias COVID-19
Cochrane Navarra - Sección de Innovación y Organización del SNS-O
From a clinical perspective, it is only possible to highlight the case series described in the study by Grein et al. (7). This uncontrolled study provides information on 53 patients analyzed with confirmation of COVID-19 and who needed supplemental oxygen supply or at least an O2 saturation of less than 95%. All received RDV through the compassionate use circuit for a maximum of 10 days, with doses of 200 mg the first day and 100 mg the following 9 days, with a follow-up of 28 days from the ...
ver más ... 2020The combination of quarantine with other prevention and control measures is recommended for an effect on the number of infections and deaths caused by COVID-19.
Evidencias COVID-19
Cochrane - Revisión rápida
29 studies were included; ten modeling studies on COVID ‐ 19, four observational studies and 15 modeling studies on SARS and MERS. Due to the various methods of measurement and analysis of the results of interest, it was not possible to carry out a meta-analysis and a narrative synthesis was written. Due to the type of evidence identified for this review, the certainty of the evidence was considered low to very low according to GRADE. Modeling studies uniformly reported a beneficial effect of ...
ver más ... 2020There is evidence of the use of personal protective equipment for the prevention of highly infectious diseases from exposure to contaminated organic liquids in healthcare personnel.
Evidencias COVID-19
Cochrane - Colección Especial - medidas de prevención y control de la infección
In addition to other infection control measures, consistent use of full‐body personal protective equipment (PPE) can diminish the risk of infection for healthcare workers (HCW). EN (European) and ISO (international) standards for protective clothing and fabric permeability for viruses are helpful to determine which PPE should technically protect sufficiently against highly infectious diseases. However, the risk of contamination depends on more than just these technical factors. In simulation ...
ver más ... 2020There is no reliable information available on the use of cotton or surgical masks to prevent the dispersion of SARS-Cov-19 particles
Evidencias COVID-19
Centro Cochrane Iberoamericano
Recent studies have shown that both exhalations, sneezing, and coughing not only contain droplets with short-range ballistic behavior, but can be composed of a multilayer turbulent gas cloud. This is important because the droplet groups would form a continuum of different sizes, and as a consequence some droplets could contaminate the surfaces, while others can evaporate producing small residues that could remain in the air for hours. Some studies in patients with COVID-19 support this ...
ver más ... 2020