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The use of dexamethasone compared to usual treatment reduces mortality in patients hospitalized with COVID-19 and in need of mechanical ventilation or oxygen therapy.
Evidencias COVID-19
Centro Cochrane Iberoamericano
The randomized clinical trial RECOVERY (Randomised Evaluation of COVid-19 theERapY) studies a series of possible therapeutic alternatives for patients hospitalized with COVID-19, including dexamethasone. The study has so far recruited more than 11,500 patients from over 175 NHS hospitals in the UK. Overall, dexamethasone was found to reduce the 28-day mortality rate by 17% with a greater benefit among those patients who required mechanical ventilation. Dexamethasone reduced mortality by up to ...
ver más ... 2020Dexamethasone administration may be useful in severe patients with Covid-19, who need oxygen supplementation or mechanical ventilation
Evidencias COVID-19
Cochrane Portugal - Institute for Evidenced Based Health
The results of this preliminary study indicate that the administration of dexamethasone decreased mortality at 28 days in patients hospitalized with Covid-19 and who needed non-invasive oxygenation or assisted ventilation. These results suggest that therapies to be used in patients with Covid-19 should be based on their initial risk. For example, remdesivir is more effective in critically ill patients, but it is unlikely that non-ventilated patients and outpatients will be treated with these ...
ver más ... 2020Psychological interventions may have positive effects to foster resilience in healthcare professionals
Evidencias COVID-19
Cochrane - Colección Especial - apoyo para el bienestar de los trabajadores sanitarios
For healthcare professionals, there is very‐low certainty evidence that, compared to control, resilience training may result in higher levels of resilience, lower levels of depression, stress or stress perception, and higher levels of certain resilience factors at post‐intervention. The paucity of medium‐ or long‐term data, heterogeneous interventions and restricted geographical distribution limit the generalisability of our results. Conclusions should therefore be drawn cautiously. ...
ver más ... 2020There is uncertainty about the psychological interventions to foster resilience in healthcare students
Evidencias COVID-19
Cochrane - Colección Especial - apoyo para el bienestar de los trabajadores sanitarios
For healthcare students, there is very‐low certainty evidence for the effect of resilience training on resilience, anxiety, and stress or stress perception at post‐intervention. The heterogeneous interventions, the paucity of short‐, medium‐ or long‐term data, and the geographical distribution restricted to high‐income countries limit the generalisability of results. Conclusions should therefore be drawn cautiously. Since the findings suggest positive effects of resilience training ...
ver más ... 2020Combined interventions have been shown to be effective and have a high impact in reducing the transmissibility of the disease, the collapse of health care services, and mortality.
Evidencias COVID-19
Unidad de Evidencia y Deliberación para la Toma de Decisiones, Facultad de Medicina - Universidad de
• Mass confinement was studied in 6 of 39 studies, reporting contradictory results on the impact of its implementation. One of these studies reports deleterious effects on the economy and another on the mental health of citizens. • The closure of schools and colleges was evaluated in 8 of 39 studies, which reported a low impact of the measure in reducing the transmissibility of the infection, the collapse of health care services, and mortality. • Regarding measures of physical distancing, ...
ver más ... 2020