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There is uncertainty as to whether combined therapy with an immunomodulatory agent and an antiviral agent is the best therapeutic option in the treatment of COVID19
Evidencias COVID-19
Evidence Aid
A total of 891 articles were found for a search, of which 289 studies were clinical studies in human, which were further evaluated in detail. Till date we do not have any definitive therapy for COVID19. We have not validated data from randomized controlled trials (RCTs) for treatment as well as for prevention for COVID19. As of today, we have more than 350 RCTs happening with different agents.
ver más ... 2020Is not recommended the use of Favipiravir against COVID-19 pending further evidence.
Evidencias COVID-19
Epistemonikos - COVID-19 L·OVE Working Group
The available evidence on favipiravir for the treatment of COVID-19 is of very low certainty. It is not possible to establish whether it is an effective drug for this disease. There are numerous ongoing studies. However, in selected critically ill patients it is weakly recommended.
ver más ... 2020There is uncertainty in psychological interventions to promote the resilience of health students.
Evidencias COVID-19
Cochrane - Colección Especial - apoyo para el bienestar de los trabajadores sanitarios
The results of a review containing 30 clinical trials conclude that the heterogeneity of interventions, the paucity of data in the short, medium and long term, and the geographic distribution restricted to high-income countries limit the generalizability of the results.
ver más ... 2020It is recommended to implement pharmacovigilance systems to ensure the safety of preventive vaccines.
Evidencias COVID-19
Cochrane Portugal - Institute for Evidenced Based Health
Through 3 clinical trials it is observed that the safety profile of the most common vaccines is excellent, the side effects are not very significant and therefore these vaccines present adequate safety.
ver más ... 2020There is a good correlation between diagnostic accuracy of symptomatic patients tested with rRT-PCR using self- collected saliva samples compared nasopharyngeal or oropharyngeal swabs
Evidencias COVID-19
NIPH Live map of COVID-19 evidence
The results indicate that the correlation between diagnostic accuracy of symptomatic patients tested with reverse transcription polymerase chain reaction (rRT-PCR) using self- collected saliva samples, compared to health care worker administrated nasopharyngeal or oropharyngeal swabs is good, corresponding to a sensitivity of 97-100 % and a specificity of 89-100%. The results should be considered with caution as further studies may change the estimates. Additionally, six of the studies are ...
ver más ... 2020