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Choosing Wisely ® : Things we do for no reason

PharmD, Barlow B.

Venous thromboembolism is positioned as one of the main and preventable causes of morbidity and mortality in hospitalized patients. Deep vein thrombosis rapidly evolves into pulmonary embolism, which account for 5% to 10% of in-hospital deaths. Negative sequelae include prolonged admissions, increased healthcare costs, and increased risk associated with pharmacological treatment. There are different recommendations that support the use of chemoprophylaxis in high-risk hospitalized patients. ...

Evidencias COVID-19

Instituto de Saúde Baseada na Evidência (ISBE)

The objectives of this rapid review were to define target levels of oxygen therapy in ARDS patients infected with SARS-CoV-2 and requiring admission to an ICU for mechanical ventilation. The impact on mortality, the duration of assisted ventilation, the number of days of catecholamine use, the need for renal replacement therapy and quality of life were analyzed. We are uncertain whether a higher or lower oxygen target is more beneficial in patients with ARDS receiving mechanical ventilation in ...

Evidencias COVID-19

Cochrane Library

The findings currently have limited applicability, as there is no certainty that testing is done in the same way in clinical practice, either based on COVID‐19 symptoms, duration of symptoms, or in asymptomatic people. Rapid tests allow for earlier detection of those who test positive. However, the current evidence is not strong enough to determine its usefulness in clinical practice.

Evidencias COVID-19

Instituto de Saúde Baseada na Evidência (ISBE)

The results indicate that the correlation between the diagnostic accuracy of symptomatic patients undergoing a PCR test with a saliva sample collected by the patients themselves, compared to nasopharyngeal or oropharyngeal swabs, collected by professionals, is good. On days 1-5 after the diagnosis of Covid-19, it was found that the percentage of positivity was higher in salivary samples (81% vs. 71%), maintaining this difference until the end of the 10-day hospitalization period. It was also ...

Evidencias COVID-19

Cochrane Iberoamérica

Coinfection was defined as bacterial pneumonia added in a patient with covid-19 in people 48–72 hours after admission for covid-19. Secondary infection was defined as cases of bacterial pneumonia 48–72 days after admission for covid-19. In general, a restrictive use of antibiotic therapy is suggested in patients with high probability or confirmation of covid-19. This is especially true for patients who have mild to moderate disease at admission (weak recommendation; very low-quality ...