The expected positive effects are a decrease in the total duration of mechanical ventilation, a decrease in the incidence of complications related to mechanical ventilation (intensive care-acquired paralysis, delirium, ventilator-acquired infections), and facilitation of early mobilization of patients. the patients.
The evidence supporting the measure is intervention studies, observational studies, meta-analyses, and recommendations from professional societies.
Studies have shown that prophylactic administration of local antibiotics does not influence the risk of endophthalmitis in case of intravitreal injections. Adequate preoperative disinfection according to international guidelines is sufficient. Reducing the use of antibiotics reduces the selection of resistant germs.
Positive serological reactions are usually the expression of a chronic infection, as occurs in a large part of the population. However, in the case of an acute primary infection, the antibody titer may still be false negative. In the case of local recurrences, neither IgM antibodies nor significant increases in IgG antibodies are usually detected
In principle, short-term application of systemic corticosteroids can relieve severe symptoms, but after discontinuation, it often threatens a rapid recurrence or even worsening (the so-called rebound effect). Long-term treatment with systemic corticosteroids may, under certain circumstances, cause serious short- and long-term side effects. Exceptions to this rule of preferring topical treatment may be severe, drug and anaphylactic reactions, as well as generalized or treatment-resistant ...
The need for and benefit of urinary catheters should be regularly discussed with patients and questioned by health professionals. Institutions must have guidelines on the indications and strategies for weaning and changing urinary catheters.