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Prescrire bilan. Towards better patient care: drugs to avoid

Prescrire International

Finasteride 1 mg, a 5-alpha reductase inhibitor, has very modest efficacy against male pattern baldness in men, slightly increasing hair density at the crown (by about 10%), but only while treatment continues. treatment. Notable side effects include sexual dysfunction (erectile dysfunction, ejaculation disorders, decreased libido), depression, suicidal ideation, and breast cancer. When a pharmacological approach is chosen, topical minoxidil is less dangerous, although certain precautions must ...

Prescrire bilan. Towards better patient care: drugs to avoid

Prescrire international

Meloxicam, piroxicam and tenoxicam are part of the nonsteroidal anti-inflammatory drugs (NSAIDs) that are used to reduce inflammation and pain in joints and muscles. When used systemically, they expose patients to an increased risk of gastrointestinal and skin disorders (including Stevens-Johnson syndrome and toxic epidermal necrolysis), but are no more effective than other NSAIDs.

Prescrire bilan. Towards better patient care: drugs to avoid

Prescrire international

Romosozumab is authorised for severe osteoporosis in postmenopausal women, on the basis of a trial in several thousand women that showed a slightly lower risk of clinical fractures than with alendronic acid. This gain must be weighed against a possible increase in the risk of cardiovascular events, with higher mortality among patients aged 75 years and older.

Smarter medicine

Sociedad Suiza de Otorrinolaringología y Cirugía Cervicofacial

In the evaluation of acute vertigo, there is a paradigm shift from an evaluation based on history and risk factors to a 3-step clinical examination, the "HINTS" test. This acronym stands for head impulse, nystagmus type, tilt test. If a central cause is suspected, brain MRI is indicated with high-resolution sections in the pontocerebellar region.

Smarter medicine

Sociedad Suiza de Otorrinolaringología y Cirugía Cervicofacial

Systemic antibiotics have significant side effects and, unlike topical antibiotic drops, do not sufficiently cover the bacteria responsible for these local infections. Furthermore, the development of resistance and the risk of opportunistic infections can be reduced by avoiding systemic antibiotic therapy.