Resultados de Búsqueda

Choosing Wisely®

American Soc. for Blood and Marrow Transplantation & the Canadian Blood and Marrow Transplant Group

Published studies have shown no advantage to using methylprednisolone-equivalent doses higher than 2 mg/kg/day in acute graft-versus-host disease. In addition, using higher doses increases risks of corticosteroid related toxicity. Furthermore, at least in patients with grade I-II acute graft-versus-host disease, initial therapy with lower-dose corticosteroids at 1 mg/kg/day may be equivalent.

Choosing Wisely®

American Soc. for Blood and Marrow Transplantation & the Canadian Blood and Marrow Transplant Group

Mientras que el injerto más rápido con células madre de sangre periférica movilizadas con filgrastim da como resultado una recuperación más rápida de los recuentos de sangre periférica en comparación con la médula ósea en pacientes con anemia aplásica, la mayor tasa de enfermedad de injerto contra huésped puede ser perjudicial.

Choosing Wisely®

American Society for Apheresis

Apheresis procedures are performed sequentially until a predefined objective goal is reached. When the goal is either achieved or is determined to be unreachable the burden and potential adverse effects of performing additional procedures outweighs the potential benefits.

Choosing Wisely®

American Society for Apheresis

For most indications, therapeutic plasma exchange can be performed on an intermittent schedule using clotting factor deficient replacement fluid without the need for routine monitoring of the patient’s hemostasis status. Daily treatments significantly reduce clotting factors; therefore, coagulation testing may be appropriate.

Choosing Wisely®

American Society for Apheresis

Stroke is a common cause of serious morbidity in children and mortality in adults with sickle cell disease. Exchange transfusion is a more effective method than simple transfusions to prevent both recurrent strokes and the complications of iron overload.