Bacterial infections of the respiratory tract, when they do occur, are generally a secondary problem caused by complications
from viral infections such as influenza. While it is often difficult to distinguish bacterial from viral sinusitis, nearly all cases are
viral. Though cases of bacterial sinusitis can benefit from antibiotics, evidence of such cases does not typically surface until
after at least seven days of illness. Not only are antibiotics rarely indicated for upper respiratory ...
Red flags include, but are not limited to, severe or progressive neurological deficits or when serious underlying conditions such as osteomyelitis are suspected. Imaging of the lower spine before six weeks does not improve outcomes.
Positive anti-TPO titres are not unusual in the ‘normal’ population. Their presence in the context of thyroid disease only
assists in indicating that the pathogenesis is probably autoimmune. As thyroid autoimmunity is a chronic condition, once
diagnosed there is rarely a need to re-measure anti-TPO titres. In euthyroid pregnant patients deemed at high risk of
developing thyroid disease, anti-TPO antibodies may influence the frequency of surveillance for hypothyroidism during the
pregnancy. ...
Many of the symptoms attributed to male hypogonadism are commonly seen in normal male aging or in the presence of
comorbid conditions. Testosterone therapy has the potential for serious side effects and represents a significant expense.
It is therefore important to confirm the clinical suspicion of hypogonadism with biochemical testing. Current guidelines
recommend the use of a total testosterone level obtained in the morning. A low level should be confirmed on a different day,
again measuring ...
T4 is converted into T3 at the cellular level in virtually all organs. Intracellular T3 levels regulate pituitary secretion and blood
levels of TSH, as well as the effects of thyroid hormone in multiple organs. Therefore, in most people a normal TSH indicates
either normal endogenous thyroid function or an adequate T4 replacement dose. TSH only becomes unreliable in patients
with suspected or known pituitary or hypothalamic disease when TSH cannot respond physiologically to altered levels of ...