There is insufficient and conflicting evidence on the effectiveness of spinal orthotics and other forms of lumbar support for treating or preventing low back pain, either as an intervention in its own right or as a supplement to other interventions.
While there is no evidence that short term bed rest is harmful, long periods of bed rest can lead to complications such as muscular atrophy. The only randomised control trial to assess optimal periods of bed rest suggests two days is as effective ...
Acute pulmonary embolism is a common cause of morbidity and mortality in older adults. Inferior vena cava (IVC) filters are frequently used to prevent subsequent PE since prior reports from administrative databases suggested their efficacy.
This study sought to determine the association between use of IVC filters and mortality rates in patients with PE using 3 distinct statistical approaches.
The results showed hypothesis-generating findings for increased risk in patients receiving IVC filters, ...
The current recommendation for adults with stable type 2 diabetes on agents that do not cause hipoglicemia is to avoid routine multiple daily self-glucose monitoring. This recommendation is based on robust evidence, including a Cochrane review of 12 randomized clinical trials with more than 3000 patients, showing no statistical difference between patients who do not self-monitor their blood glucose multiple times per day and those who do self-monitor their blood glucose multiple times per day ...
Clinical research has focused on parenteral anticoagulation as a potential therapeutic intervention in patients with non–ST-segment elevation acute coronary syndrome (NSTE-ACS). Clinical trials with such medication reported clinical benefit, and consequently clinical practice guidelines recommend the immediate use of these agents in all patients with NSTE-ACS.
This observational study seeks to evaluate whether parenteral anticoagulation therapy adds significantly to modern approaches to ...
Cochrane - Colección Especial - Opciones efectivas para dejar de fumar durante la pandemia COVID-19
NRTs increase the rate of quitting by 50% to 60%, regardless of setting, and further research is very unlikely to change our confidence in the estimate of the effect. The relative effectiveness of NRT appears to be largely independent of the intensity of additional support provided to the individual. Provision of more intense levels of support, although beneficial in facilitating the likelihood of quitting, is not essential to the success of NRT. NRT often causes minor irritation of the site ...