Resultados de Búsqueda

Evidencias COVID-19

Cochrane Navarra - Sección de Innovación y Organización del SNS-O

- The combination of antivirals lopinavir-ritonavir (LPV / r) has shown efficacy in vitro and in animal models against the SARS-CoV and MERS-CoV viruses. - The LOTUS China study is the first clinical trial to explore the efficacy and safety of LPV / r in patients with COVID-19 infection and associated pneumonia. The trial has failed to demonstrate that the addition of LPV / r to standard care provides a clinical benefit in the analyzed patient profile. - Several clinical trials investigating ...

Evidencias COVID-19

Cochrane Navarra - Sección de Innovación y Organización del SNS-O

- There is currently no validated effective treatment for COVID-19. - Chloroquine and hydroxychloroquine have shown in vitro efficacy against COVID-19, but to date, the available data do not confirm their usefulness in the clinic. - Currently, we have information from three clinical trials (two not yet published) and three studies with observational design (one not yet published). - Two of the clinical trials show no benefits with hydroxychloroquine compared to standard care. A third clinical ...

Evidencias COVID-19

Centro Cochrane Iberoamericano

- The adverse effects associated with the treatments administered to patients with COVID-19 are relatively frequent and can intensify with this disease. - Most of the adverse effects reported to the French ANSM have been serious, with a notable proportion of cardiac adverse effects, many associated with treatment with hydroxychloroquine (alone or in combination with azithromycin).

Evidencias COVID-19

Coronavirus (COVID-19): Evidence Collection. Evidence Aid

Any setting which brings a large number of people into regular contact is an environment in which a respiratory infectious disease, such as COVID-19, can easily spread. Prison is such a setting and evidence on using custodial or non-custodial sentences may inform policies about imprisoning people convicted of a crime. In this Campbell systematic review, the authors searched for research that compared the effects of custodial and non‐custodial sentences on re‐offending. They did not restrict ...

Evidencias COVID-19

Coronavirus (COVID-19): Evidence Collection. Evidence Aid

As research is done to develop or identify diagnostic tests, vaccines and treatments for COVID-19, multiple rapid reviews are being done of these topics. In this rapid systematic review, the authors searched for randomized trials and validation trials for diagnostic tests evaluating rapid diagnostic tests, the impact of drug therapy and vaccine efficacy for coronaviruses generally. In addition, for COVID-19 specifically, they searched for in vitro, animal or human studies published in English ...