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There is no certainty to recommend high versus low positive end‐expiratory pressure (PEEP) levels for mechanically ventilated adult patients with acute lung injury and acute respiratory distress ...
Evidencias COVID-19
Cochrane - Colección Especial - cuidados críticos (asistencia respiratoria y ventilación mecánica)
In summary, the present systematic review provides evidence that the use of high levels of PEEP does not reduce mortality before hospital discharge, although the forest plot indicated a trend towards a mortality benefit in the higher‐PEEP group. Moreover, in practice, we cannot recommend the routine use of high levels of PEEP in patients with ALI and ARDS because no agreement has been reached among the various studies reported here as to which group of patients should receive that specific ...
ver más ... 2013Penicillin/ampicillin plus gentamicin over chloramphenicol is recommended for hospitalized children with severe and very severe community-acquired pneumonia.
Evidencias COVID-19
Cochrane - Colección Especial - cuidados críticos (tratamiento farmacológico)
The other alternative drugs for children hospitalised with severe and very severe community-acquired pneumonia are co‐amoxyclavulanic acid and cefuroxime. Until more studies are available, these can be used as second‐line therapies. For treatment of patients with community-acquired pneumonia in ambulatory settings, amoxycillin is an alternative to co‐trimoxazole. With limited data on other antibiotics, co‐amoxyclavulanic acid and cefpodoxime may be alternative second‐line drugs. ...
ver más ... 2013The case for adopting the EXOGEN ultrasound bone healing system to treat long bone fractures with non-union (failure to heal after 9 months) is supported by the clinical evidence, which shows high ...
NICE
National Institute for Health and Clinical Excellence (NICE)
The EXOGEN ultrasound bone healing system to treat long bone fractures with non-union is associated with an estimated cost saving of £2,407 per patient compared with current management, through avoiding surgery. [2019] There is some radiological evidence of improved healing when the EXOGEN ultrasound bone healing system is used for long bone fractures with delayed healing (no radiological evidence of healing after approximately 3 months). There are substantial uncertainties about the rate at ...
ver más ... 2013It is potentially not recommended to order imaging for suspected pulmonary embolism in low risk patients without the use of a diagnostic evidence-based algorithm.
Too Much Medicine - theBMJ [Demasiada Medicina-TheBMJ]
Wiener R. BMJ 2013;347:f5131
For further information please visit the website of the initiative (link below)
ver más ... 2013Attention-deficit/hyperactivity disorder (ADHD) drug makers move to expand into adult market
Too Much Medicine - theBMJ [Demasiada Medicina-TheBMJ]
McCarthy M. BMJ 2013;347:f7581
For further information please visit the website of the initiative (link below)
ver más ... 2013