Remdesivir has been suggested as a treatment for patients with COVID-19 but at the time of this review, the available evidence suggested that remdesivir probably has little or no effect on all-cause mortality through 28 days in hospitalized patients with COVID-19. Furthermore, the effects of remdesivir on clinical improvement and worsening, and across subgroups defined by respiratory support at baseline are uncertain.
The authors of this Cochrane review search for randomized trials of ...
U.S. Preventive Services Task Force A and B recommendations
U.S Preventive Services Task Force
Dental caries is the most common chronic disease in children in the US.1-3 According to the 2011-2016 National Health and Nutrition Examination Survey, approximately 23% of children aged 2 to 5 years had dental caries in their primary teeth.4 Prevalence is higher in Mexican American children (33%) and non-Hispanic Black children (28%) than in non-Hispanic White children (18%).5 Dental caries in early childhood is associated with pain, loss of teeth, impaired growth, decreased weight gain, ...
The mitral valve allows blood to flow from the left atrium to the left ventricle. Mitral valve regurgitation happens when the valve does not close properly and blood flows back into the atrium from the ventricle. The heart has to work harder to pump blood from the left ventricle to the aorta, resulting in an enlarged left ventricle. If not treated, this can lead to shortness of breath, fatigue and palpitations (because of atrial fibrillation) and eventually heart failure. If symptoms of mitral ...
U.S. Preventive Services Task Force A and B recommendations
U.S. Preventive Services Task Force
The USPSTF concludes that the current evidence is insufficient to assess the balance of benefits and harms of screening for vitamin D deficiency in asymptomatic adults.
For asymptomatic, community-dwelling, nonpregnant adults, the USPSTF found that the evidence is insufficient to assess the balance of benefits and harms of screening for vitamin D deficiency. More research is needed.
Essencial: Afegint valor a la pràctica clínica [Essencial: Adding value to the clinical practice]
Sociedad Catalana de Psiquiatría y Salud Mental
Antipsychotic drugs are an essential component of the treatment of patients with schizophrenia.
The combination of antipsychotics is associated with a higher burden of adverse effects, specifically in terms of extrapyramidal symptoms, cognitive alterations, hyperprolactinemia, sedation, sexual dysfunction, metabolic symptoms, and diabetes.
The combination of antipsychotics should be reserved for cases of resistance to clozapine or when it has not been tolerated.
There is no available evidence ...