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Cochrane Quality and Productivity topics

National Institute for Health and Clinical Excellence (NICE)

"Use of epoetin (also known as EPO) may reduce the use of blood transfusions but not sufficiently to reduce donor exposure. Use of epoetin appears to lead to an increase in the incidence of retinopathy of prematurity (ROP). As such the Cochrane review determined that the use of epoetin is not recommended."

Cochrane Quality and Productivity topics

National Institute for Health and Clinical Excellence (NICE)

"Post-dural puncture headaches are a recognised complication of any procedure where the dura is punctured. The dural puncture may be intentional, with the use of a spinal needle, or unintentional, as a complication of epidural injections or catheterisations. It is thought that cerebrospinal fluid (CSF) leakage through the puncture hole is a key determinant of whether a headache develops, so it was thought that bed rest would reduce fluid leakage by reducing the hydrostatic pressure at the ...

Cochrane Quality and Productivity topics

National Institute for Health and Clinical Excellence (NICE)

"NICE summary of review conclusions

Antigen-specific active immunotherapy for ovarian cancer is not supported by sufficient good quality evidence. Consideration could be given to using it only within the context of a research or audit project. Reducing or stopping antigen-specific active immunotherapy for ovarian cancer is likely to improve the quality of patient care by reducing exposure to unproven therapies and result in productivity savings.

The Implications for ...

Choosing Wisely Canada

Canadian Urological Association - Canadian Medical Association - University of Toronto

Ultrasound is of minimal value in localizing the position or existence of testes that cannot be felt through physical examination. Studies have shown that there remained a significant chance that testes were present even after a negative ultrasound result. The likelihood of locating testes is low when using ultrasound.

Choosing Wisely Canada

Canadian Urological Association - Canadian Medical Association - University of Toronto

Studies suggest that asymptomatic bacteriuria in the elderly does not carry significant risk of morbidity if left untreated. Antimicrobial treatment studies for asymptomatic bacteriuria in older adults demonstrate no benefits and show increased adverse antimicrobial effects. Consensus criteria has been developed to characterize the specific clinical symptoms that, when associated with bacteriuria, define urinary tract infection. Screening for and treatment of asymptomatic bacteriuria is ...