Cochrane - Colección Especial - Coronavirus (Covid-19): asistencia en remoto mediante la telesalud
This result should be confirmed in future studies evaluating efficacy through consistent randomized controlled studies and aspects of experience using qualitative studies with abundant data.
Coronavirus (COVID-19): Evidence Collection. Evidence Aid
Nine of the included trials compared different antibiotics and, hence, we could not combine the results of the individual trials to present our overall conclusion. There were some notable adverse events in seven studies: 1) erythromycin demonstrated significant gastrointestinal side effects compared to clarithromycin in two studies; 2) nemonoxacin demonstrated higher gastrointestinal (nausea, diarrhoea) and nervous system (dizziness, headache) adverse events compared to levofloxacin; 3) ...
Coronavirus (COVID-19): Evidence Collection. Evidence Aid
Some patients with COVID-19 will become critically ill and need help with their breathing. This might be provided by mechanical ventilation (MV) in an intensive care unit (ICU). Clinicians use a variety of methods to bring people off MV as they recover, including formal weaning protocols.
In this Cochrane systematic review, the authors searched for randomized and quasi-randomized trials of the effects of weaning protocols on reducing the time that critically ill patients spend on MV. They did ...
we did not have strong evidence that daily sedation interruption reduced the duration of mechanical ventilation, length of stay in the intensive care unit (ICU) or hospital, death, or the amount of drug used. The effect on adverse events such as accidental removal of the breathing tube or invasive devices, or the rate of delirium was uncertain. However, tracheostomy was performed less often in those who were managed with daily sedation interruption. Sedation practices are known to vary ...
Cochrane - Colección Especial - cuidados críticos (desconexión de la ventilación mecánica)
Its suggest the reduced duration of mechanical ventilation, weaning duration and ICU length of stay with use of standardized weaning protocols. Reductions are most likely to occur in medical, surgical and mixed ICUs, but not in neurosurgical ICUs. However, significant heterogeneity among studies indicates caution in generalizing results. Some study authors suggest that organizational context may influence outcomes, however these factors were not considered in all included studies and could not ...