National Institute for Health and Clinical Excellence (NICE)
There is no good evidence that flushing central venous catheters (CVCs) with heparin is better than flushing with normal saline solution (sodium choride 0.9%). Heparin may cause undesirable side effects and gives no benefit over normal saline, which has virtually no side effects. Heparin did not offer additional protective effects against complications associated with CVC use; namely, sepsis, thrombosis and haemorrhage. Therefore, intermittent flushing of CVCs with heparin is not recommended.
The Canadian Task Force for Preventive Health Care Guidelines
Public Health Agency of Canada, PHAC
This recommendation applies to community dwelling older adults (≥65 years of age) who do not have noticeable symptoms suggestive of mild cognitive impairment or dementia. This recommendation does not apply to men or women who are concerned about their own cognitive performance (i.e. the patient has raised complaints about cognitive changes with their clinician or others) or who are suspected of having mild cognitive impairment or dementia by clinicians or non-clinicians (caregivers, family, ...