Melanoma is the fifth most common skin cancer in the UK. The earliest stage melanomas are stage 0 (melanoma in situ), and then range from stages I (1) through IV (4). Some stages are split further, using capital letters.
Diagnostic testing to identify patients with BRAF-mutant melanoma who may benefit from vemurafenib treatment is not recommended in patients with stages IA and IB.
Consider BRAF analysis of melanoma tissue samples from people with stage IIA or IIB primary melanoma.
Perform BRAF ...
For women between 22+0 and 23+6 weeks of pregnancy who are in suspected or established preterm labour, are having a planned preterm birth or have P‑PROM, discuss with the woman (and her family members or carers, as appropriate) and the multidisciplinary team the use of maternal corticosteroids in the context of her individual circumstances.
Consider a single repeat course of maternal corticosteroids for women less than 34+0 weeks of pregnancy who:
- have already had a course of ...
Coronavirus (COVID-19): Evidence Collection. Evidence Aid
Infection prevention and control interventions are especially important during the COVID-19 pandemic. Sodium hypochlorite is used as a disinfectant to reduce the spread of hospital-acquired infections. In this systematic review, the authors searched for studies that compared the effects of sodium hypochlorite with those other disinfectant products or different concentrations of hypochlorite on the prevention of hospital-acquired infections. They did not restrict their search by date, type or ...
Coronavirus (COVID-19): Evidence Collection. Evidence Aid
Infection prevention and control interventions are important in healthcare settings, particularly during the COVID-19 pandemic. Existing research on the efficacy of using alcohol as a disinfectant might provide useful information for policy makers. In this systematic review, the authors searched for research evaluating the disinfection of semi-critical healthcare materials (such as respiratory and anaesthesia equipment, endoscopes, and dental drills) with 60–80% alcohol (w/v), with and ...
Coronavirus (COVID-19): Evidence Collection. Evidence Aid
The COVID-19 pandemic is placing a strain on healthcare services. The involvement of medical scribes to enter information into electronic health records (EHRs) during healthcare encounters may improve productivity and limit disruption to patient-physician interactions.
In this systematic review the authors searched for effectiveness studies of medical scribes on healthcare productivity, quality and outcomes. They limited their search to studies published in English between 2000 and 2014. Five ...