A semi-recumbent position (≧ 30 °) can reduce clinically presumed NAR compared to the supine position from 0 ° to 10 °. However, the tests have important limitations, with a high risk of bias. Insufficient evidence is available to draw definitive conclusions about other outcomes or to compare alternate semi-recumbent positions. Adverse events, particularly venous thromboembolism, were insufficiently reported.
Significant clinical heterogeneity was identified in the 10 included trials. Results are based on findings from several trials (five) that included an "expanded lung respiratory support strategy", whereby the intervention group was different from the control group in addition to the re-expansion maneuver (including co-interventions such as PPFE higher, different modalities of respiratory assistance and higher plateau pressure), making it difficult to interpret the results. A respiratory support ...
Coronavirus (COVID-19): Evidence Collection. Evidence Aid
Some patients with COVID-19 will become critically ill and may develop hypotensive shock, but there is uncertainty about the most beneficial way to treat this. Vasopressors have shown evidence of benefit in hypotensive shock, probably because of their ability to raise blood pressure. Their effects for patients with hypotensive shock caused by other factors might indicate their effects in patients with COVID-19.
In this Cochrane systematic review, the authors searched for randomized trials ...
Coronavirus (COVID-19): Evidence Collection. Evidence Aid
Some patients with COVID-19 will become critically ill and may develop hypotensive shock, but there is uncertainty about the most beneficial way to treat this. Vasopressors have shown evidence of benefit in hypotensive shock, probably because of their ability to raise blood pressure. Their effects for patients with hypotensive shock caused by other factors might indicate their effects in patients with COVID-19.
In this Cochrane systematic review, the authors searched for randomized trials ...
Coronavirus (COVID-19): Evidence Collection. Evidence Aid
Some patients with COVID-19 will develop respiratory failure and need help with their breathing. This might be provided by mechanical ventilation (MV) in an intensive care unit (ICU), but this can cause complications, including ventilator-associated pneumonia (VAP). A semi-recumbent position (also known as “head bed elevation”) may prevent VAP in comparison to a supine position.
In this Cochrane systematic review, the authors included randomized trials that compared semi-recumbent versus ...