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Cochrane Quality and Productivity topics

National Institute for Health and Clinical Excellence (NICE)

NICE summary of review conclusions The use of antibiotics in acute laryngitis has not been shown objectively to have any significant clinical benefit that can justify this use in clinical practice. Despite an overall paucity of evidence, treating acute laryngitis with conservative measures in the first instance is appropriate because antibiotics are associated with side effects and an increased incidence of antimicrobial resistance, which is costly and harmful to the population as a whole. Not ...

Cochrane Quality and Productivity topics

National Institute for Health and Clinical Excellence (NICE)

NICE summary of Cochrane review conclusions Evidence does not support the use of ursodeoxycholic acid (UDCA) for the prevention of cystic fibrosis (CF)-related liver disease. Many of the studies performed to date failed to include important outcomes (for example, number of liver transplants), and showed no significant improvement in the normalisation of any single hepatocellular enzyme, increase in weight or improvement in biliary excretion with the use of UDCA. Therefore at present UDCA cannot ...

Cochrane Quality and Productivity topics

National Institute for Health and Clinical Excellence (NICE)

NICE summary of Cochrane review conclusions Evidence does not support the routine use of inhaled corticosteroids (ICS) as anti-inflammatory agents in children and adults with cystic fibrosis (CF). There is no evidence of objective improvements in lung function or subjective improvements in exercise tolerance or quality of life. ICS should only be used for the symptomatic relief of recurrent wheezing that is not responsive to bronchodilators alone. Outside of this indication they are likely to ...

Choosing Wisely Australia

Australasian Faculty of Occupational and Environmental Medicine

Asbestosis usually takes years to decades to develop after the initial exposure and chest X-rays cannot immediately indicate whether or not asbestos fibres have been inhaled. Given the long latency period, screening and early detection of asbestosis by chest X-ray is unlikely to confer any health advantage or psychological benefit on asbestos-exposed individuals. Moreover, there is now evidence that low-dose multi-detector CT (MDCT) rather than chest X-ray is justified for initial examination ...

Choosing Wisely Australia

Australasian Faculty of Occupational and Environmental Medicine

While some medical conditions necessitate time off work, for example, a person recovering from surgery or experiencing debilitating pain, with many medical conditions there is a substantial discretionary element to work absence. So some patients may be able to participate in work if employers make appropriate accommodations. There is substantial evidence to support a positive link between work and (physical, mental and social) health, as well as evidence that absence from work contributes to ...