Choosing Wisely Italy. Doing more does not mean doing better (Fare di più non significa fare meglio)
Italian Federation of Primary Care Pediatricians (FIMP)
Bronchiolitis is the most common infection of the lower respiratory tract in children less than 1 year of age. It is caused by a virus, the most common is respiratory syncytial virus (RSV). Most of children affected by bronchiolitis usually heal spontaneously. Despite their common use, there is no evidence that bronchodilators and/or corticosteroids (nebulized or by oral route) are useful to slow the course of the disease or to avoid hospitalization, neither there are other effective ...
Choosing Wisely Italy. Doing more does not mean doing better (Fare di più non significa fare meglio)
SIPMeL – Study Group on Autoimmune Diseases
The finding of even one antibody positivity among anti-GAD, anti-IA2 and anti-ZnT8 is a diagnostic criterion of LADA and suggests an autoimmune pathogenesis in gestational diabetes mellitus.
Choosing Wisely Italy. Doing more does not mean doing better (Fare di più non significa fare meglio)
SIPMeL – Study Group on Autoimmune Diseases
In the presence of gastric function compatible with atrophy and autoantibody positivity the suspicion is substantial and it is necessary to proceed to gastric biopsy.
Choosing Wisely Italy. Doing more does not mean doing better (Fare di più non significa fare meglio)
SIPMeL – Study Group on Autoimmune Diseases
The determination of anti-Musk antibodies should be reserved for anti-AChR negative patients, while that of anti-Lrp4 antibodies should be limited to anti-AChR and anti-MuSK negative patients.
Since the three autoantibodies are mutually exclusive, it is not useful to simultaneously request the determination of all three antibodies, because about 80% of patients with myasthenia have only anti-AChR, 16% only anti-MuSK and the remaining 4% only anti-Lrp4 antibodies.