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Refer urgently children who present with discrete episodes of loss of awareness (mid-activity vacant spells) or of attention and concentration difficulty, in line with the NICE guideline on ...
NICE
National Institute for Health and Clinical Excellence (NICE)
Be aware that medicines commonly used to treat epilepsy in children can adversely affect concentration and memory. The committee noted that concentration and memory problems are common in children who have diagnosed or undiagnosed epilepsy. They agreed that, in a child not diagnosed with epilepsy, episodes of loss of awareness, attention or concentration might be unrecognised absence seizures that need further investigation.
ver más ... 2019Refer urgently adults with new-onset blackouts (transient loss of consciousness), accompanied by features that are strongly suggestive of epileptic seizures, for neurological assessment in line with ...
NICE
National Institute for Health and Clinical Excellence (NICE)
Do not routinely refer adults with blackouts if there are clear features of vasovagal syncope, even if associated with brief jerking of the limbs. See recommendation 1.1.4.3 on uncomplicated faint in the NICE guideline on transient loss of consciousness ('blackouts') in over 16s. The committee agreed that the NICE guideline on transient loss of consciousness ('blackouts') in over 16s provides comprehensive recommendations on recognition and referral.
ver más ... 2019Irreversible electroporations is not recommended for human therapy. This procedure should only can be used in the context of research. Evidence on the safety of irreversible electroporation for ...
NICE
National Institute for Health and Clinical Excellence (NICE)
Patient selection should be done by a multidisciplinary team. The procedure should only be done in specialist centres by clinicians with experience and specific training. Further research could be in the form of case series or registry-based research. It should include: details of patient selection; tumour position and size; long-term outcomes including overall survival, progression-free survival and tumour regression; and patient-reported outcomes including quality of life.
ver más ... 2019Regorafenib is recommended as an option for treating advanced unresectable hepatocellular carcinoma in adults who have had sorafenib, only if they have Child–Pugh grade A liver impairment and an ...
NICE
National Institute for Health and Clinical Excellence (NICE)
This recommendation is not intended to affect treatment with regorafenib that was started in the NHS before this guidance was published. People having treatment outside this recommendation may continue without change to the funding arrangements in place for them before this guidance was published, until they and their NHS clinician consider it appropriate to stop. Advanced unresectable hepatocellular carcinoma is mostly treated with sorafenib in the NHS. For people who cannot tolerate ...
ver más ... 2019Lenalidomide is recommended as an option, within its marketing authorisation, that is for treating transfusion‑dependent anaemia caused by low or intermediate‑1 risk myelodysplastic syndromes ...
NICE
National Institute for Health and Clinical Excellence (NICE)
No further information.
ver más ... 2019