The evidence on the safety and efficacy of endobronchial nerve ablation for chronic obstructive pulmonary disease (COPD) is quantitatively inadequate. Therefore, this procedure should only be performed in the context of research.
COPD affects mostly middle-aged and older adults; and the main cause is smoking. Although the lung damage caused by COPD is permanent, treatment can help slow the progression of the disease. Treatments include smoking cessation, pulmonary rehabilitation, inhaled ...
Uterine fibroids (also known as leiomyomas or uterine fibroids) are benign tumors of the uterus. They can be asymptomatic or cause symptoms including heavy periods or bleeding between periods. They may be associated with fertility problems and miscarriage. Evidence on the safety of hysteroscopic mechanical tissue removal (hysteroscopic morcellation) for uterine fibroids shows that there are well-recognized, rare, but potentially serious side effects. The evidence on its efficacy is limited in ...
Although no major short-term safety problems have been found after genicular artery embolization for knee osteoarthritis pain, the evidence on its long-term efficacy and safety is inadequate in quality and quantity. That is why it is only recommended for investigational use in randomized controlled trials against sham and current best practice. This process should only be performed by interventional radiologists with specific training in this technique.
The incidence of rectal cancer increases with age. Treatment consists of resection of the affected part of the rectum with preservation of the anus or, when this is not possible, a colostomy. Complementary radiotherapy and chemotherapy may also be used.
The aim of transanal total mesorectal excision is to improve the clinical outcome of rectal resection and to reduce the length of hospital stay and morbidity after surgery. As for the safety evidence of the technique, it is inconsistent: there ...
Evidence on the safety of laparoscopic removal of uterine fibroids with electrical morcellation shows potentially serious complications. In particular, there is a risk of spreading undiagnosed malignant tissue, which is more prevalent in people who are postmenopausal or older than 50 years. The evidence on the efficacy of the procedure is limited in quantity.
For persons who are premenopausal or age 50 and younger, this procedure should only be used with special arrangements for clinical ...